
學(xué)歷:博士研究生
學(xué)科:生物化工
部門:1823組
電話:0411-84771060
郵箱:zhouyongjin@dicp.ac.cn
地址:大連市中山路457號
? ? ? 周雍進,男,博士,研究員,博士生導(dǎo)師。2006年于江南大學(xué)獲得食品科學(xué)與工程學(xué)士學(xué)位;2008 年于天津大學(xué)獲得生物化工碩士學(xué)位;2012年于中國科學(xué)院大連化學(xué)物理研究所獲得生物化工博士學(xué)位;2012-2016年在瑞典查爾姆斯理工大學(xué)從事博士后研究。2017年引進回到中國科學(xué)院大連化物所建立合成微生物學(xué)研究組,受聘為研究組組長。曾在Cell、Nature Energy、Nature?Metabolism、Nature Chemical Biology、JACS、PNAS、Nature Communications等期刊發(fā)表論文90余篇。曾獲2021年張大煜優(yōu)秀學(xué)者,2018年“倫世儀教育基金”杰出青年學(xué)者獎,2015年中國藥學(xué)會科學(xué)技術(shù)獎一等獎,2016國際代謝科學(xué)會議青年科學(xué)家獎。
主要研究方向是微生物合成生物學(xué)和代謝工程。
? ? ? 主要研究興趣為:1)甲醇等一碳資源生物轉(zhuǎn)化;2)微生物細胞反應(yīng)器構(gòu)建及優(yōu)化;3)天然產(chǎn)物生物合成。詳情請見課題組主頁。
1. Shan Yang, Ruibing Chen, Xuan Cao, Guodong Wang, Yongjin Zhou*, De novo?biosynthesis of the hops bioactive flavonoid xanthohumol in yeast, Nature Communications, 2024, 15, 253.
2. Jiaoqi?Gao#, Wei Yu#, Yunxia Li, Mingjie Jin, Lun Yao, Yongjin Zhou*, Engineering co-utilization of glucose and xylose for chemical overproduction from lignocellulose, Nature Chemical Biology, 2023, 19, 1524-1531.
3. Xiaoxin Zhai, Jiaoqi Gao, Yunxia Li, Martin Grininger, Yongjin Zhou*, Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast, Proceedings of the National Academy of Sciences of the United States of America, 2023, 120(12), e2220816120.
4. Min Ye, Jiaoqi Gao, Yongjin Zhou*, Global metabolic rewiring of the nonconventional yeast Ogataea polymorpha?for biosynthesis of the sesquiterpenoid β-elemene, Metabolic Engineering, 2023, 76, 225-231.
5. Jiaoqi Gao, Yunxia Li, Wei Yu, Yongjin Zhou*, Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol, Nature Metabolism, 2022, 4, 932-943.
6. Peng Cai, Xiaoyan Wu, Jun Deng, Yongjin Zhou*, Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast?Pichia pastoris, Proceedings of the National Academy of Sciences of the United States of America, 2022, 119(29), e2201711119.
7. Ruibing Chen, Jiaoqi Gao, Wei Yu, Xianghui Chen, Xiaoxin Zhai, Yu Chen, Lei Zhang*, Yongjin Zhou*, Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast. Nature Chemical Biology, 2022, 18(5), 520-529.
8. Peng Cai#, Xingpeng Duan#, Xiaoyan Wu, Linhui Gao, Min Ye, Yongjin Zhou*, Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia pastoris. Nucleic Acids Research, 2021, 49(13), 7791–7805
9. Tao Yu#, Yongjin Zhou#, Mingtao Huang, Quanli Liu, Rui Pereira, Florian David, Jens Nielsen*, Reprogramming yeast metabolism from alcoholic fermentation to lipogenesis. Cell. 2018, 174(6), 1549-1558.
10. Yongjin Zhou, Eduard Kerkhoven, Jens Nielsen*, Barriers and opportunities in bio-based production of hydrocarbons. Nature Energy, 2018, 3, 925-935.